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ea0029p562 | Diabetes | ICEECE2012

High prevalence of autoimmunity in adult onset diabetes subjects with high GADA titre

Zampetti S , Capizzi M , Spoletini M , Campagna G , Cipolloni L , Petrone A , Tiberti C , Di Pietro S , Locatelli M , Falorni A , Bosi E , Buzzetti R , Nirad Study Group (Italian Society of Diabetes)

Introduction: LADA is a heterogeneous population of diabetes subjects wherein subgroups can be identified based on their autoimmune status: the titre of autoantibodies to GAD.The aim of the study was to correlate, in LADA subjects, GADA titre, with the presence of other organ and non organ specific autoantibodies.Methods: LADA subjects (n=191) and type 2 diabetes (T2DM) subjects (n=382) were selected from the Non Insu...

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ea0029p547 | Diabetes | ICEECE2012

High GADA titre: a marker of insulin dependence in adult onset autoimmune diabetes

Spoletini M. , Zampetti S. , Capizzi M. , Tiberti C. , Venditti C. , Campagna G. , Bosi E. , Buzzetti R. , Italian Society of Diabetes Nirad Study Group

Introduction: In latent autoimmune diabetes of adults (LADA), the progression to insulin-dependent diabetes is usually faster than in type 2 diabetes (T2DM) but the factors influencing this progression are not completely known. The aim of the present study was to determine whether GADA could be used as predictors of insulin dependence and whether GADA titre could define the risk of progression to insulin therapy in LADA patients. We looked for other biochemical and clinical pa...

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Endocrine Abstracts

High prevalence of autoimmunity in adult onset diabetes subjects with high GADA titre

High GADA titre: a marker of insulin dependence in adult onset autoimmune diabetes

BiosciAbstracts